The Use of Pamidronate to Treat Arthritis

One of the treatment programs that you can have for arthritis is Pamidronate. The brand name for this product is Aredia and it has been one of the popular alternatives for patients with this condition. It falls within the bisphosphonates in terms of its chemical composition. Sometimes people forget that bones are living tissues. New bones are created as old ones die away. A failure to balance the creation of new bones with older bones can create the ideal conditions for arthritis to prosper. Therefore it is important to access treatment early so that some of the more painful symptoms are alleviated. Apart from arthritis, this form of treatment is used against Paget’s disease. The method of application is through an injection and it can therefore be prescribed for patients who do not tolerate other forms of bisphosphonate.

Groups of patients that might benefit from pamidronate

The use of pamidronate has been associated with women who develop osteoporosis after menopause. It might be also used to complement the corticosteroids that are used to deal with rheumatic arthritis. It prevents fractures and other injuries which are typical of this condition. The disease activity in Paget’s disease will be significantly reduced. Patients that have high blood calcium levels may be given this treatment in order to bring their levels down. This is an essential method for dealing with certain types of cancers. The treatment is provided through the administration of a slow injection in a vein. This method is known as intravenous infusion within medical circles. It is imperative that the infusions are given under medical supervision within a hospital setting. The infusion process can last up to one hour depending on the dosage and the reactions by the patient. The condition will then gradually respond to the treatment which has been provided.

The infusions will be given every three months in cases of osteoporosis. They could be continued on a permanent basis if the patient is responding well to them. In cases of Paget’s disease, the patient and doctor will come to a reasonable schedule for the infusions. The course will normally last from four weeks to eight weeks. Of course the infusions of Pamidronate will be repeated if the condition flares up in due course. The primary objective is to ensure that the patient has the best care possible in all circumstances. Patients might also be advised to take vitamin D and calcium in order to improve the state of their bone structures. In osteoporosis cases Pamidronate will start to work in twelve months. The area that will be targeted is bone density. With Paget’s disease the time frame for the medication to work is about three to six months.

The side effects include a mild fever. This will occur at the beginning of the treatment but only lasts for a maximum of forty eight hours. Sometimes the patient will develop flu-like symptoms including shivering and a sore throat. It is important that Pamidronate is taken under the supervision of a clinician so that the side effects can be dealt with effectively.

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