The commercial name for Golimumab is Simponi and it is one of the leading treatments for arthritis. Classified under the anti TNF class or anti tumor necrosis factors, this is one of the most effect ways to deal with other inflammatory diseases. The lists of potential cases that use this treatment include psoriatic arthritis and ankylosing spondylitis. In most cases it is prescribed to adults with any of the conditions. The arthritis has to be active before the prescription will be given. If you are taking another DMARD drug such as hydroxychloroquine or sulfasalazine, then Golimumab will not be prescribed. Patients with psoriatic arthritis will need to first start off with methotrexate before this sort of treatment. Pregnant and breastfeeding women should not take this medication because it could possibly harm the baby. Likewise you should not take Golimumab if you have an infection.
The proper application of Golimumab
A consultant rheumatologist will be able to give you the prescription that you need. The medication is taken through a subcutaneous injection. That means that you can administer it on a DIY basis or train a family member to help you. The injections are given on the thigh or tummy depending on the practicality of the location. The Golimumab that is offered to patients comes in a pre filled syringe or pen of about fifty milligrams. It is given on a monthly basis. A biological therapy alert card may be needed in order to help people that are dealing with an emergency where you are involved. If you forget to take the dosage then you should go back to the plan the moment you remember. The schedule can be reactivated according to the way that you want to take the medication.
The response rate is not instantaneous but quite good when compared to other similar types of medication. You will expect the first positive results within about fourteen weeks of your initial dosage. That is where you will have take about four injections of Golimumab. Where the patient weights more than one hundred kilograms then the doctor may consider increase the dosage slightly. The site of the injection may suffer from redness and swelling. However the more serious reactions happen as a consequence of interference in the immune system. You will be vulnerable to opportunistic infections. That means that you need to take precautions to keep out of harm’s way.
The precautions when you use Golimumab
First of all you will need to watch out for food poisoning. Avoid eating raw foods if you do not know the source of those foods. Make sure that your leftovers are properly refrigerated and that you warm them up to the correct temperature. You might also want to increase the general standards of hygiene within the home in order to reduce the possibility of developing food poisoning in the future. Those are the preventative measures that are expected if you are undergoing a course of Golimumab. It will help you to feel healthier and will reduce the risk of opportunistic infections.
The use of the gold by intramuscular injection is a well known method for treating some of the symptoms that are associated with arthritis. The development of the condition is effectively controlled while at the same time the body is given time to recover within the various stages of recovery. The reason for these prescriptions is to reduce inflammation. It will also help to reduce the pain that is associated with arthritis. Apart from rheumatoid arthritis these gold by intramuscular injection can be used to treat psoriatic arthritis.
The proper administration of this arthritis treatment
Patients will start off with the injection on a weekly basis. It is recommended that this is administered at the GP surgery or a local hospital. The gold by intramuscular injection is administered on the buttock. A small test dosage may be used to ensure that there are no adverse reactions from the use of the active ingredients. The content within these injections will come up to about fifty milligrams of gold. As the condition improves then the frequency of the gold by intramuscular injection may be reduced to once a fortnight. There are times where the treatment will be so successful that you will no longer need an injection outside the monthly dosage that is made available. This treatment is capable of being used on a long term basis without any serious side effects on the patient.
It is not common for the patient to react to the gold by intramuscular injection. In many instances the patient will be held back for thirty minutes after the first dose in order to ascertain how they are coping with the treatment. If there are indications that they are reacting badly then the treatment might be postponed for another day. It is imperative that these injections are given in the most suitable conditions and that the patient is comfortable with the treatment. It would be difficult to sustain this form of treatment if there were adverse reactions. After about twelve weeks the first signs of recovery should be evident unless there is a specific problem with the treatment program. It has been reported that gold causes problem with the blood flow and could affect the kidney. It might also make the skin worse in the long run. The doctor or rheumatology nurse should be kept informed about the development in the patient’s condition.
The effects of the gold by intramuscular injection
The adverse effects of the gold by intramuscular injection may include a skin rash, breathlessness and mouth ulcers. Patients could find that their taste buds are not working as well as they usually due. These are just average side effects but you many have specific reactions that are not seen in other parts of the population. That is why this treatment should be done under the supervision of a properly qualified clinician. It is the least you can to do to ensure that there is a possibility for quick recovery. In the end that will make a difference to the way that you deal with the situation.
One of the most reliable medical treatments for arthritis is Etanercept. This sort of medication is only available after you have secured a prescription from your family doctor. The method of application is through a subcutaneous injection which is given twice a week. Patients should carry a biological therapy card in case they are involved in an accident. The medication works within twelve weeks. In some fortunate cases the effects will be felt within a matter of two weeks. The basic side effects that are due to this medication include dizziness, headache, a rash, stomach pain and indigestion. The injection site may also become inflamed. The severity of these side effects will directly determine how you respond to the condition in the first place.
Care for patients on Etanercept
There are specific considerations when looking after patients taking Etanercept. First of all the person giving care has to keep a record of major reactions so that the physicians are able to make a correct diagnosis of what is happening. The doctor might wish to have some X-Ray test taken prior to recommending the treatment. They will also want to have blood tests. This drug is sometimes prescribed together with other medication including methotrexate. Doctors have to be aware of all the medication that you are taking so that they can make an informed judgment on the risk of drug interactions.
It has to be understood that Etanercept is not a pain killer and therefore should not be used in that vein. Even where you are merely taking herbal remedies, it is a good idea to consult with your doctor. Some of these remedies can end up making matters worse. The doctor will then explain to you if there are any risks associated with the type of medication that you are taking. Other patients will take Etanercept with Pneumovax. This is a wonderful protective substance against the most common types of pneumonia. It is possible to drink alcohol while you are taking Etanercept. Nonetheless this combination should not be added to methotrexate. This is because interaction can arise and there will be damage to your liver in the long run. Immediately after surgery, the doctor may advise that the intake of Etanercept has to be held back for a while.
Other issues with Etanercept
It is not yet clear whether Etanercept can adversely affect an unborn baby. In the absence of such conclusive evidence, women should be very cautious about the way that they use the product. It is also advisable to keep away from the drug if you are breastfeeding. This is because the drug can pass through the milk to the child’s system. It could be a danger to the child and it is better not to take the risk. The use of Etanercept is primarily focused on arthritis. Nonetheless there has to be some consideration of the personal circumstances of the patient. Nothing should be done to make matters worse. It is imperative that you take the correct dosage of Etanercept according to the prescription.
Many patients are given a prescription for Cyclophosphamide and it helps them to cope with all sorts of arthritis. It works by modifying the disease. This medication is taken on three levels according to the severity of the condition that they are treating. At the first level is the low dosage of about tablets that are taken once a day. On the second level is the high dosage with a few powerful tablets that are taken every few weeks. At the highest level, the Cyclophosphamide is taken in an intravenous injection. Patients are advised to take the medication after a meal. The early morning or afternoon is the preferred time to take the medication. You should swallow the medication whole and not make an attempt to chew it.
Setting the right level of treatment with Cyclophosphamide
This medication is not likely to work immediately. You might see the full results in about six weeks time. Therefore patients and their families need to be patient. The pain and inflammation will not disappear overnight. Many people that take Cyclophosphamide say that nausea is almost inevitable. It is possible to control this and the doctor will be able to give you medication for this purpose. The bladder wall may become inflamed and start bleeding when you are on this medication. That is why it is imperative that you report any symptoms to your doctor. It has been suggested that drinking up to ten glasses of water a day will help to combat this problem.
The doctor may prescribe Mesna to go with the Cyclophosphamide in order to ensure that the patient does not suffer from cystitis. If you take this medication on a long term basis, there could be a significant reduction in your blood count. This essentially means that you are producing fewer blood cells. That might result in higher infection rates than in the normal population. A sore throat and fever after taking Cyclophosphamide are just some of the more serious side effects which might require clinical intervention. Prior to prescribing the medication, the doctor might want to undertake some tests on the bladder and your blood. This will ensure that they are making decisions that are going to hurt you in the future. It is imperative that the medical history of the patient is kept in one place. Failure to do so will have serious implications.
Using Cyclophosphamide as part of a combination therapy
Before using herbal remedies it is important that you check with your family doctor. These remedies may conflict with the work that Cyclophosphamide is supposed to do. In the worst case scenario you might end up with negative reactions. Where you are taking the medication, the recommendation is not to take live vaccines such as that for yellow fever. The medication tends to compromise your immunity system and you might end up developing the condition which you wanted to get rid of. Generally speaking Cyclophosphamide is safe to use and has been recommended by many people who are experienced in treating arthritis.
The commercial name for Ciclosporin is Neoral. This is one of the diseases modifying anti rheumatic drugs that are gaining in popularity today. In cases of rheumatoid arthritis, this medication is used to reduce swelling and stiffness. Ultimately it will reduce the amount of pain that the patient has to suffer during the duration of arthritis. The use of Ciclosporin has been extended to lupus erythematosus and systemic psoriatic arthritis. The medication is taken in the form of a capsule that is swallowed twice a day. There are liquid versions of Ciclosporin which might act as an effective alternative. The doctor will tell you about the correct dosage for this medication and you are advised to follow the instructions that they set. Body weight and the state of your kidneys will be one of the considerations that the doctor looks at.
Ciclosporin and its medical uses
Patients are advised not to take grapefruit juice within one hour of the medication. This is because the grapefruit juice tends to increase the level of natural Ciclosporin in the body. That means that if you add the synthetic version then you are essentially opening the doors to an overdose. That is not the way that it is supposed to be and a patient that ignores this instruction might end up with serious side effects in the long run. This is not one of those medications that work immediately. It might take months before you get the results that you are looking for. The side effects include an increase in the patient’s blood pressure. They might also have an impact on the function of the kidney. The level of lipids within the body might rise so that the user faces a cholesterol problem.
Other pronounced side effects might include diarrhoea, nausea, gum overgrowth, headache, excessive hair, tiredness, tremors and burning sensations on the body. The impact on the gums is very pronounced and that is why patients that are taking Ciclosporin are advised to visit the dentist on a fairly regular basis. If the symptoms become severe then you should stop the medication with immediate effect. Where you develop shingles or chicken pox, then it is clear that the medication has compromised your immune system. It is advisable to stop taking the medication. Alternatively you might keep away from situations where you can get opportunistic diseases. The clinician that is handling the case will need to look at the blood and urine tests in order to ascertain whether it is still safe to give her
Taking care while using Ciclosporin
It is important that you discuss your medication regime with the family doctor. They can normally make important recommendations on the best course of action. They are also in a position to decide on whether the risk of drug reactions exists. Do not go over the dose just because the pain has increased. The proper course of action is to make an appointment with the doctor and explain to them the kinds of symptoms that you are getting. They will then be in a position to make a decision as to whether the dosage of Ciclosporin should be increased.
The brand name for Certolizumab pegol is Cimzia. It is one of the anti TNF medications which are known as anti tumor necrosis factors. It specifically targets the inflammation that is normally associated with rheumatoid arthritis. The prescription is normally restricted to the cases where the arthritis is active. The clinician will also ensure that other forms of medication such methotrexate have been looked at. Alternatively you might be given sulfasalazine and hydroxychloroquine. It is only when these options prove to be unworkable that the clinician will move on to prescribing Certolizumab pegol. There are some contra indications for the treatment including inactive arthritis, pregnancy, breastfeeding and sundry infections.
Using Certolizumab pegol safely
It is important that you follow the advice that is provided by the clinician when using Certolizumab pegol. They have your best interests at heart. They also understand some of the negative side effects that can arise if you do not take this medication carefully enough. People that have suffered from TB or MS in the past are excluded from this form of treatment. Likewise people that have cancer will not be able to use Certolizumab pegol on account of the negative impact that it might have on their general health. Patients with lung fibrosis or heart conditions should look for alternatives to this medication. The medication is taken by use of a subcutaneous injection. You might want to get a member of your family to help you with the injections once they receive the right instructions.
Normally the doses are put in a pre filled syringe for your convenience. The syringe will have about 200 milligrams of the medication. The starting point is about 400 mg every two weeks. This can then be gradually increased as the body begins to adjust to the new treatment program. In addition patients should carry a biological therapy alert card just in case they are caught up in an emergency where the attendants require this information in order to do their work properly. The response rate for Certolizumab pegol is between two and twelve weeks. Some of the side effects include irritation on the injection site. It also has an effect on the immune system. Therefore patients might develop a sore throat or a fever.
A sensible approach to Certolizumab pegol
The usage of Certolizumab pegol might suppress your immune system such that you become susceptible to food poisoning. Some of the bugs that disturb you may include listeria and salmonella. In order to minimize this risk you should eat less of raw eggs, unpasteurized milk, cheese and rare meat. All types of pate should be off the menu given their association with food poisoning. You need to ensure that there are basis hygiene standards in the home so that you are not exposed to risks. The situation on your reaction to Certolizumab pegol will have to be monitored by the family doctor. There could be periods where the side effects flare up on a temporary basis. You should try to use the drug sensibly.
One of the disease modifying medications that are used for arthritis patients is Azathioprine. It is an anti rheumatic drug that falls under the DMARD category. When patients take this drug it dampens the progress of the condition. Rather than concentrating on the management of the symptoms, this medication goes to the heart of the problem by targeting the underlying condition. It acts by reducing the functionality of the immune system. This is a dangerous course of action and therefore you need the approval of your doctor. If the immune system is diminished significantly then the patient may become ill due to opportunistic diseases.
Using Azathioprine to treat arthritis
The medication will be prescribed for different types of rheumatic disease such as arthritis and systemic lupus erythematosus or SLE. If a patient is already on steroid treatment, Azathioprine might be included in the treatment program in order to start the process of taking out the steroids. In arthritis patients the medication is taken in the form of one tablet twice a day. The dosage could be reduced or increased according to the medical needs of the patients. This is a clinical judgment that must not be based on speculation alone. The doctor has to examine the patient and come to a conclusion as to where they are going to take the medication. It is advisable to take the tablet after a meal.
This is not fast acting medication unless the patient is experiencing the placebo effect. However between six and twelve weeks, the first signs of the improvement will be seen. In terms of side effects, some patients have experiences nausea as well as actual vomiting. They may develop diarrhea or skin rashes. The loss of hair and an appetite can be very devastating for the patient. It can affect the level and lead to other opportunistic infections that can greatly reduce the quality of life that the patient leads in the long run. Clinical intervention may be required where the patient develops fever, a sore throat, bleeding, jaundice and bruising. If patients develop shingles or chicken pox, then they should stop the medication immediately.
Care when taking Azathioprine
This sort of medication is capable of compromising your immune system. Therefore it is important that patients consult with their doctor before taking Azathioprine. There have been studies that link Azathioprine to certain forms of cancer. Therefore you have to be very careful when taking this sort of medication. Patients that are already suffering from immune deficiencies should not use Azathioprine or they could end up on the emergency table. This type of medication is only used as a temporary form of intervention. You cannot spend the rest of your life on Azathioprine. That is why doctors are very strict about the people that receive this form of treatment. It is important that all prescriptions are strictly controlled. You also need to work out methods through which you can find complementary medicine. This might be the thing that is required to keep your body in good shape.
One of the most common tricyclic antidepressants is Amitriptyline. Nevertheless it can also be used in the treatment of arthritis or the symptoms of such a condition. It is important that the dosage is controlled because it determines the condition which is targeted. At the higher levels Amitriptyline can be an antidepressant while at the lower levels it is used to manage arthritis. Patients should be mindful of the advice that is given by their family doctor before taking on this type of medication. There can be very serious implications if the medication is taken without proper prescription. It could end up causing long term damage to the patient. For patients with arthritis, this drug can reduce pain and increase the possibility that the patient can sleep. On the other hand it might reduce the anxiety and depression that arthritis patients can suffer from.
The value of Amitriptyline in the treatment of arthritis
Patients who have been referred to a rheumatology pain clinic might be prescribed Amitriptyline in order to reduce the symptoms that they are suffering from. It is normally associated with treating chronic pain. The pain sources could include spinal disorders as well as arthritis. Pain amplification can occur when there is a disconnection with the nervous system. The work of Amitriptyline is to rebalance the chemicals within the nervous system so that the patient ends up feeling less pain in the long run. The medication is available in the form of syrup or tablets. The patient may feely sleepy after taking the medication. Therefore it is best to take this medication just before you go to bed.
The doctor that has prescribed Amitriptyline will be in a position to tell the patient about the maximum dosage. For chronic pain the typical daily dosage is about 5-50 mg per day. The patient will start on a low dose and then work until they are at a pain level which is bearable. The patient should avoid being dependent on the medication on a long term basis because it tends to cause more problems than solutions. Normally the patient will sleep immediately after taking Amitriptyline but the impact on the pain will take a longer period of time. The most common side effect of the medication is a dry mouth. The patient may feel drowsy or disoriented. It is important they do not drive after taking the medication. In some cases the side effects reduce with time.
Other side effects that arise from Amitriptyline
Patients may experience difficulty in passing urine. You may also experience constipation and an irregular heartbeat. If you have high blood pressure then Amitriptyline will make you feel dizzy. This symptom tends to get worse in older patients. Epileptic patients will find that they have an increased number of seizures following the medication. Glaucoma and blurred vision may arise due to the pressure on the eyes. These are rare but very serious symptoms. Therefore you need to arrest them at the earliest opportunity. Your doctor should be involved in the search for solutions.
One of the most common drugs for arthritis is Allopurinol. In technical terms this is known as a xanthine oxidase inhibitor. The body will produce uric acid which is carried through the blood system as urate. The kidneys are responsible for getting rid of this salt through the passage of urine. Too much urate can build up on the joints and cause gout. The intake of Allopurinol will help to reduce the rate at which uric acid is formed in the body. That way that arthritis patient will be given some relief from their symptoms. This medication can be prescribed on a long term basis to prevent the development of gout or to even reduce the symptoms of gout if the patient has already jumped that particular ship.
The prescription of Allopurinol to manage arthritis
Where there is an acute attack of gout then the limitations of Allopurinol are self evident. The primary purpose of the medication is to prevent the accumulation of excess crystals within the body system. Normally the doctor will require blood tests in order to ascertain the development of the condition within the blood stream. Therefore the prescription will be based on facts rather than speculation. It is possible to remove the symptoms of gout or to prevent its progression if you use this medication correctly. The medication is taken in the form of a tablet. Patients are advised to take the Allopurinol tablet once a day and it is preferred that the patient first consumes food before taking the medication. You should swallow the tablet with water.
It is advisable not to take Allopurinol unless any acute attacks have completely settled. The manufactured tablets come in batches with 100 mg and 300 mg strength tablets. A maximum limit of 300 mg is recommended on average although there are cases where the doctor will recommend a higher dosage depending on the reactions of the patient. If the patient is suffering from liver disease or kidney disease then the lower dosage will be recommended for their safety. Surprisingly taking Allopurinol can trigger gout in the first few months before settling down. Therefore doctors might prescribe another form of medication in order to combat these symptoms. In this case NSAIDs are the preferred. One of the branded medications for this purpose is colchicine.
The specific requirements when using allopurinol
If you develop a case of severe gout when using Allopurinol then it is not advisable to stop the medication. You should continue as normal but then treat the symptoms so that the quality of life for the patient is improved in the long run. There will be a significant reduction in the urate levels within the blood after a few weeks of taking the medication. When the crystals are completely dissolved then it is possible to have relief from gout. In some instances it will take a year for the full impact of the treatment to take place. The vast majority of patients do not experience negative side effects when they take Allopurinol. On certain occasions the patient may develop a minor rash. If this becomes serious then medical attention should be sought.
One of the most important courses of medication that may be administered to an arthritis patient is Adalimumab. The brand name for this product is Humira and it is available on a commercial basis. It falls within the category of drugs that are known as anti tumor necrosis factors or TNF. In cases where the patient is suffering from rheumatoid arthritis or RA, there might be an overload of the TNF protein. This will lead to damage within the cartilage, bones and general tissue. The use of Adalimumab can reduce inflammation in general terms but sometimes patients need medication that targets specific symptoms that they are experiencing as part of the progression in the condition. The prescription of Adalimumab is based on the development of rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis. Children with idiopathic arthritis or JIA (JCA) may be prescribed this medication.
The use of Adalimumab in practical terms
The arthritis has to be active before the prescription is approved. In cases of RA the doctors will first begin with methotrexate and then progress to DMARD medication. Some of the branded medication may include gold injections and Sulfasalazine. It is only when these forms of treatment are impossible that the doctor will consider the progression to Adalimumab. Women who are pregnant or breastfeeding are not prescribed this medicine because it tends to get into the breast milk and adversely affects the baby. An infection might be a contra indication for Adalimumab. For example ex tuberculosis patients might be excluded. The same rule applies to people with multiple sclerosis. Cancer patients are advised not to take Adalimumab. Likewise people with cardiac problems or lung infections should stay away from the medication.
The medication is only available through prescription on the advice of a rheumatologist. The dosage is about forty milligrams per fortnight. It might be administered through a subcutaneous injection. Where patients are trained or if their families have been instructed, these injections could be administered from home. A district may administer the injections if the immediate is unable to undertake the task. Patients that are on this medication should carry the relevant biological therapy alert card. In that sense, the emergency services will be aware of the existence of another form of medication in your system. The initial responses should occur between two and twelve weeks after starting the course of medication.
Side effects and implications of using Adalimumab
Some patients have reported local reactions near the skin where an injection has been administered. For example they may develop swelling, redness and pain. Nonetheless these symptoms are not serious enough to warrant medical attention. On a far more serious note, the use of Adalimumab might affect the immune system. Therefore the patient may develop infections and it is imperative that the clinician handling the case is informed at the earliest opportunity. If there are serious problems with the administration of Adalimumab then it is imperative that the family doctor is given this information. They can look for better alternatives for the patient.